I have quite a bit of experience with the Leatherique twins. They have been my go to for my seats for the last few years.
If you have used the Leatherique twins on your leather seats, you obviously finished up with the Prestine Clean. If you want to use 303 after the Prestine Clean, you obviously can. The 303 will dress and lay down some protection. In my opinion and experience though 303 leaves a slick surface that I don't care for. For me Leatherique twins leave the seats just how I want them and I want to try and keep them just like that for as long as possible.
I prefer other matte products like Optimum Leather Protectant,
Megs QID, 1Z Einszett Leather Care (not great for perforated seats), WG Trim Sealant.