I have a general purpose cleaning bottle which gets aimed at, wheels, wheel wells, heavily soiled areas... hose off, apply suds, repeat, wipe down with costco mf & #34, toss mf.
My current recipe:
32oz bottle - rubbermaid sprayer head
mostly water
1/2oz Simple Green ( more if target surface is badly soiled )
1/2oz Meguiar's APC
1/8oz S100 Total Cycle Cleaner
(( 1/2oz. of Charlies APC )) also works well
My wheel wells are plastic in the front and carpet in the back, too much APC will cause a swilly or catty smell, so less is more, I don't expend my precious brush fiber on my wheel wells, plus the fit is kinda tight, heavy stream for carpet, mist for plastic.
The beater(s) pressure wash, but gently.