I've used the No. 2 with a PC DA. It's similar to FI-2 in some ways. I also believe the Meguiars vid on-line also has them using a DA with FC but it's been awhile since I've seen it.
Just make sure to work it long enough and you'll be fine. Follow-up with No. 9 as I didn't get as high a gloss to the finish as I would like to have after No. 2 alone.
The medium cut I would be hesistant against though with a DA.
Paco
edit: FYI: Posted by 2wheelsX2 in the "Similar Products" thread:
I think DACP is very simiar to Finess-It II, but is a bit milder. #2 Fine Cut compound is not very useful. I have used it, and it's really not much harsher than SMR (which is a bit more aggressive than #9). I think of that line, the Medium Cut cleaner (can't remember the number, #3 maybe?) would be closer to FI-II.