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<em class='bbc'>Originally posted by Intel486 [/i]
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I'd have to pretty much strip the truck down and reinforce the chassis.
I'd also be pretty much rebuilding the whole drive train. Transmission, rear end, drive shaft, etc.
The cost is a lot though. I can either do this to my truck or get a second truck
Edit: You think a 600hp engine with no nitrous would twist my frame? [/b]</blockquote>
Yep. You would need to stiffen the frame in order to handle the increased hp. Since Pickups have a structure that is not very rigid in the rear, the added torque will cause chassis flex/twist. Also, you would need to consider ladder bars in order to ensure you have some traction off the line.
As far as the rear end goes, I would get one from a F-350 tow truck but modify it to handle the increased torque as well as reduce the gearing so that you aren't lighting up tires every time you start.